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CS-W001157 4
Total: USD 88.00

Metformin

  • CAS No. 657-24-9

  • Cat. No. CS-0009563
  • Purity≥97%
  • MDL No.MFCD00242652

*For research and further manufacturing use only, not for direct human use.

Metformin|CS-0009563

Structure of 657-24-9

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General Information

  • CAS No. 657-24-9
  • Cat. No. CS-0009563
  • Purity ≥97%
  • MDL No. MFCD00242652
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁N₅
  • Molecular Weight 129.17
  • Synonym(s) 1,1-Dimethylbiguanide
  • SMILES NC(NC(N(C)C)=N)=N

Application

Metformin serves as a well-established biguanide scaffold for medicinal chemistry and metabolic research, enabling rapid access to bioactive heterocyclic systems. Its robust functional group tolerance and stability under physiological conditions facilitate direct incorporation into drug discovery campaigns. The molecule functions as a reliable building block in the synthesis of novel antidiabetic agents and related pharmacophores, offering predictable reactivity and straightforward purification.

Synthesis

  • Route1

    References

    • Veisi, Hojat; Khazaei, Ardeshir; Safaei, Maryam; Kordestani, Davood Journal of Molecular Catalysis A: Chemical, 2014 , vol. 382, p. 106 - 113
  • Route2
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      1378856-94-0
    • ~%
    • In-stock
      Metformin|CS-0009563
      657-24-9

    References

    • Journal of Molecular Structure, , vol. 996, # 1-3 p. 38 - 41
  • Route3
    • null|null
      1170667-82-9
    • ~%
    • In-stock
      Metformin|CS-0009563
      657-24-9

    References

    • WO2010/100337 A1, ; Page/Page column 9 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   88.99
  • LogP   -1.03416
  • H_Acceptors   2
  • H_Donors   4
  • Rotatable_Bonds   0

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