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Structure of 654-87-5
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2,3,5-Trifluorobenzoic acid delivers a potent electron-withdrawing profile due to three fluorine atoms positioned ortho and para to the carboxyl group. This configuration enhances acidity and stability, enabling efficient coupling reactions in pharmaceutical synthesis. The molecule's rigidity and polar character support precise molecular design in medicinal chemistry applications.
2,3,5-Trifluorobenzoic acid serves as a versatile building block in medicinal chemistry and materials science, offering enhanced metabolic stability and modulated lipophilicity due to its three strategically positioned fluorine atoms. The carboxylic acid functionality enables direct coupling reactions, including amide formation and esterification, while the trifluorinated aromatic core provides robust bench stability and favorable solubility profiles for downstream synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: