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CS-W001157 4
Total: USD 88.00

5-Aminoisobenzofuran-1(3H)-one

  • CAS No. 65399-05-5

  • Cat. No. CS-0059293
  • Purity≥95%
  • MDL No.MFCD00778315

*For research and further manufacturing use only, not for direct human use.

5-Aminoisobenzofuran-1(3H)-one|CS-0059293

Structure of 65399-05-5

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General Information

  • CAS No. 65399-05-5
  • Cat. No. CS-0059293
  • Purity ≥95%
  • MDL No. MFCD00778315
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₂
  • Molecular Weight None
  • Synonym(s) 5-Aminophthalide
  • SMILES O=C1OCC2=C1C=CC(N)=C2

Description

5-Aminoisobenzofuran-1(3H)-one features a fused bicyclic core with an electron-rich amine substituent, enabling direct incorporation into heterocyclic scaffolds. The compound exhibits enhanced solubility and stability under standard conditions, facilitating use in medicinal chemistry and materials synthesis workflows.

Application

5-Aminoisobenzofuran-1(3H)-one serves as a versatile scaffold for heterocyclic synthesis, offering a stable platform for derivatization at the amine and carbonyl sites. Its fused ring system exhibits favorable bench stability and compatibility with standard coupling reactions, facilitating access to complex molecular architectures. Functions as a building block in medicinal chemistry campaigns targeting bioactive molecules requiring rigid, planar frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H412
Precautionary Statements : P264-P270-P273-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.9392
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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