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Structure of 6526-08-5
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2-Amino-5-(trifluoromethyl)benzonitrile features a trifluoromethyl group that imparts strong electron-withdrawing character and enhanced metabolic stability, while the amino and nitrile functionalities enable versatile coupling reactions. This compound serves as a key building block in medicinal chemistry for synthesizing bioactive heterocycles and functional materials under standard conditions.
2-Amino-5-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds through standard coupling and cyclization protocols. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the amino and nitrile functionalities provide orthogonal reactivity for downstream functionalization. The compound exhibits good bench stability and is amenable to purification via recrystallization or column chromatography, facilitating integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: