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CS-W001157 4
Total: USD 88.00

Isosorbide

  • CAS No. 652-67-5

  • Cat. No. CS-5157
  • Molecule weightNone
  • Purity≥96%
  • MDL No.MFCD00064827

*For research and further manufacturing use only, not for direct human use.

Isosorbide|CS-5157

Structure of 652-67-5

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General Information

  • CAS No. 652-67-5
  • Cat. No. CS-5157
  • Purity ≥96%
  • MDL No. MFCD00064827
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₄
  • Molecular Weight None
  • Synonym(s) D-Isosorbide; Dianhydro-D-glucitol
  • SMILES O[C@H]1[C@]2([H])[C@]([C@@H](O)CO2)([H])OC1

Description

Dianhydro-D-glucitol is a greener ingredient widely used as a monomer and building block for a variety of polymers and functional materials, for medical and pharmaceutical applications. It is also used as a fuel or fuel additive.Applications include:Preparation of renewable polyesters for coating applications.Synthesis of isosorbide esters such as oligo(isosorbide adipate) (OSA), oligo(isosorbide suberate) (OSS), and isosorbide dihexanoate (SDH) as renewable alternatives to phthalate plasticizers.Synthesis of biodegradable porous polyurethane scaffolds for tissue repair and regeneration.Synthesis of the aspirin prodrug, isosorbide-2,5-diaspirinate (ISDA).

Synthesis

  • Route1

    References

    • US2008/33187 A1, ; Page/Page column 8; 9 ;
  • Route2

    References

    • Li, Ning; Huber, George W. Journal of Catalysis, 2010 , vol. 270, # 1 p. 48 - 59
  • Route3

    References

    • E. I. DU PONT DE NEMOURS AND COMPANY Patent: WO2003/89436 A1, 2003 ; Location in patent: Page/Page column 21-23 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   -1.4942
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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