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CS-W001157 4
Total: USD 88.00

2-Bromo-3-methoxypropanoic acid

  • CAS No. 65090-78-0

  • Cat. No. CS-0197352
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-3-methoxypropanoic acid|CS-0197352

Structure of 65090-78-0

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Description

2-Bromo-3-methoxypropanoic acid features a bromine atom at the α-position and a methoxy group at the β-carbon, enabling selective functionalization in synthetic routes. This configuration supports efficient coupling reactions and facilitates incorporation into bioactive scaffolds under mild conditions. The molecule exhibits enhanced stability and solubility in polar organic media, simplifying handling during process development workflows.

Application

2-Bromo-3-methoxypropanoic acid serves as a versatile building block for β-halo ester and α,β-unsaturated carbonyl synthesis. Its bromine and methoxy functionalities enable sequential functionalization via nucleophilic substitution or elimination reactions, facilitating access to medicinally relevant heterocyclic scaffolds. The compound exhibits good bench stability and is compatible with standard purification techniques, supporting reliable use in multi-step synthetic sequences.

General Information

  • CAS No. 65090-78-0
  • Cat. No. CS-0197352
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BrO₃
  • Molecular Weight 183.00
  • Synonym(s) 2-Bromo-3-methoxypropionic acid
  • SMILES O=C(O)C(Br)COC

Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.4809
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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