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CS-W001157 4
Total: USD 88.00

3-Chloro-4-fluorobenzoyl Chloride

  • CAS No. 65055-17-6

  • Cat. No. CS-0622479
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Chloro-4-fluorobenzoyl Chloride|CS-0622479

Structure of 65055-17-6

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General Information

  • CAS No. 65055-17-6
  • Cat. No. CS-0622479
  • Purity ≥97%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃Cl₂FO
  • Molecular Weight 193.00
  • Synonym(s) None
  • SMILES C1=CC(=C(C=C1C(=O)Cl)Cl)F

Description

3-Chloro-4-fluorobenzoyl chloride is a reactive acylating agent featuring a chlorinated and fluorinated aromatic ring, enabling selective coupling in pharmaceutical synthesis. This bench-stable reagent integrates efficiently into amide bond formation workflows under standard conditions.

Application

3-Chloro-4-fluorobenzoyl chloride serves as a versatile acylating agent for the synthesis of aryl ketones and amides, enabling efficient incorporation of the 3-chloro-4-fluorophenyl moiety into target molecules. Its reactivity is well-suited for standard coupling protocols, with good bench stability and ease of purification. Functions effectively in nucleophilic acyl substitution reactions, particularly in the construction of pharmaceutical intermediates and functionalized heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2923
Class : 8 (6.1)
Packing Group : Ⅲ
Hazard Statements : H301-H311-H314-H331
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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