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CS-W001157 4
Total: USD 88.00

2-Isopropylbenzaldehyde

  • CAS No. 6502-22-3

  • Cat. No. CS-W019200
  • Molecule weight148.20
  • Purity≥96%
  • MDL No.MFCD06201222

*For research and further manufacturing use only, not for direct human use.

2-Isopropylbenzaldehyde|CS-W019200

Structure of 6502-22-3

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General Information

  • CAS No. 6502-22-3
  • Cat. No. CS-W019200
  • Purity ≥96%
  • MDL No. MFCD06201222
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O
  • Molecular Weight 148.20
  • Synonym(s) o-Isopropylbenzaldehyde
  • SMILES O=CC1=CC=CC=C1C(C)C

Description

2-Isopropylbenzaldehyde features a para-substituted aromatic ring with an isopropyl group flanking a reactive aldehyde moiety. This electron-rich scaffold enables direct integration into Suzuki-Miyaura couplings and reductive amination workflows under standard conditions. The sterically hindered isopropyl substituent enhances regioselectivity in electrophilic aromatic substitution reactions.

Application

2-Isopropylbenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aromatic scaffolds. Its aldehyde functionality facilitates standard transformations including nucleophilic additions, reductive amination, and condensation reactions. The ortho-isopropyl group provides steric and electronic modulation, enhancing regioselectivity in electrophilic substitutions and improving bench stability for handling and purification. This compound functions effectively in the synthesis of pharmaceutical intermediates and agrochemicals requiring substituted benzaldehyde motifs.

Synthesis

  • Route1
    • In-stock
      1-Bromo-2-isopropylbenzene|CS-W019560
      7073-94-1
    • null|null
      68-12-2
    • ~84%
    • In-stock
      2-Isopropylbenzaldehyde|CS-W019200
      6502-22-3

    References

    • Sugiura, Hiroki; Sakai, Daisuke; Otani, Harunori; Teranishi, Kazuhiro; Takahira, Yusuke; Amemiya, Ryo; Yamaguchi, Masahiko Chemistry Letters, 2007 , vol. 36, # 1 p. 72 - 73
  • Route2
    • In-stock
      o-Cymene|CS-0368263
      527-84-4
    • ~14%
    • In-stock
      2-Isopropylbenzaldehyde|CS-W019200
      6502-22-3
    • null|null
      128260-56-0
    • null|null
      128260-55-9

    References

    • Tetrahedron, , vol. 45, # 23 p. 7545 - 7552
  • Route3
    • 1-(Chloromethyl)-2-isopropylbenzene|CS-0724302
      20034-71-3
    • ~90%
    • In-stock
      2-Isopropylbenzaldehyde|CS-W019200
      6502-22-3

    References

    • Liu, Qifa; Lu, Ming; Sun, Feng; Li, Jiang; Zhao, Yuebing Synthetic Communications, 2008 , vol. 38, # 23 p. 4188 - 4197

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.6225
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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