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CS-W001157 4
Total: USD 88.00

4-Chloro-2-(chloromethyl)-6-methylpyrimidine

  • CAS No. 64994-45-2

  • Cat. No. CS-0231200
  • Molecule weight177.03
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Chloro-2-(chloromethyl)-6-methylpyrimidine|CS-0231200

Structure of 64994-45-2

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General Information

  • CAS No. 64994-45-2
  • Cat. No. CS-0231200
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆Cl₂N₂
  • Molecular Weight 177.03
  • Synonym(s) Pyrimidine,4-chloro-2-(chloromethyl)-6-methyl
  • SMILES CC1=CC(=NC(=N1)CCl)Cl

Synthesis

  • Route1
    • 2-(Chloromethyl)-6-methyl-1H-pyrimidin-4-one|CS-0036596
      23862-02-4
    • ~%
    • 4-Chloro-2-(chloromethyl)-6-methylpyrimidine|CS-0231200
      64994-45-2

    References

    • Sumitomo Chemical Company, Limited Patent: US4326058 A1, 1982 ;
  • Route2
    • 2-(Hydroxymethyl)-6-methylpyrimidin-4-ol|CS-0282255
      33796-42-8
    • ~96%
    • 4-Chloro-2-(chloromethyl)-6-methylpyrimidine|CS-0231200
      64994-45-2

    References

    • Shvachkin, Yu. P.; Krasnoshchekova, S. P.; Nikitina, A. M.; Anokhina, T. M. Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 11 p. 621 - 621 Khimiko-Farmatsevticheskii Zhurnal, 1998 , vol. 32, # 11 p. 53 - 53
  • Route3

    References

    • Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H335
Precautionary Statements : P260-P261-P264-P271-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.17722
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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