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CS-W001157 4
Total: USD 88.00

2,4-Dichloro-5-iodoaniline

  • CAS No. 647025-63-6

  • Cat. No. CS-0698065
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,4-Dichloro-5-iodoaniline|CS-0698065

Structure of 647025-63-6

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General Information

  • CAS No. 647025-63-6
  • Cat. No. CS-0698065
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄Cl₂IN
  • Molecular Weight 287.91
  • Synonym(s) None
  • SMILES NC1=CC(I)=C(Cl)C=C1Cl

Description

2,4-Dichloro-5-iodoaniline features a highly halogenated aromatic core with complementary reactivity at the iodine and amine sites. This electron-deficient aniline derivative enables direct coupling in cross-coupling protocols and serves as a key intermediate in the synthesis of functionalized pharmaceuticals and agrochemicals.

Application

2,4-Dichloro-5-iodoaniline serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its ortho-chloro and para-iodo substituents enable selective cross-coupling reactions, while the aniline functionality offers compatibility with standard protecting group strategies. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.1802
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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