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Structure of 647025-62-5
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4-Fluoro-3-iodoaniline features a strategically positioned fluorine and iodine substituent on the aromatic ring, enabling efficient cross-coupling transformations. The electron-withdrawing fluorine enhances reactivity in palladium-catalyzed reactions, while the iodide serves as a high-affinity coupling handle. This dual-functional scaffold supports rapid diversification in medicinal chemistry and materials synthesis.
4-Fluoro-3-iodoaniline serves as a versatile building block for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The ortho-iodo group exhibits high reactivity under standard coupling conditions, while the para-fluoro substituent provides synthetic handle for further functionalization. Bench-stable and readily purified by recrystallization, it functions reliably in medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: