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CS-W001157 4
Total: USD 88.00

1-Methyl-2,3-dihydro-1H-inden-1-ol

  • CAS No. 64666-42-8

  • Cat. No. CS-0047056
  • Purity≥95%
  • MDL No.MFCD12067606

*For research and further manufacturing use only, not for direct human use.

1-Methyl-2,3-dihydro-1H-inden-1-ol|CS-0047056

Structure of 64666-42-8

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General Information

  • CAS No. 64666-42-8
  • Cat. No. CS-0047056
  • Purity ≥95%
  • MDL No. MFCD12067606
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O
  • Molecular Weight None
  • Synonym(s) 1-Methyl-2,3-Dihydro-1H-Inden-1-Ol(WX644012)
  • SMILES OC1(C2=CC=CC=C2CC1)C

Description

1-Methyl-2,3-dihydro-1H-inden-1-ol offers a rigid, fused bicyclic scaffold with a secondary alcohol at the bridgehead position, enabling direct functionalization without ring strain. This bench-stable, moisture-tolerant compound integrates readily into synthetic sequences requiring defined stereochemistry and steric control.

Application

1-Methyl-2,3-dihydro-1H-inden-1-ol serves as a versatile chiral building block in synthetic organic chemistry, enabling efficient access to indane-based scaffolds. Its tertiary alcohol functionality offers reliable site-specific derivatization, while the rigid bicyclic framework imparts structural stability and predictable stereochemical behavior. The compound exhibits excellent bench stability and compatibility with common functional group transformations, facilitating its use in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      917-54-4
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0
    • ~90%
    • In-stock
      1-Methyl-2,3-dihydro-1H-inden-1-ol|CS-0047056
      64666-42-8

    References

    • Wuensch, Thomas; Meyers, A. I. Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4233 - 4235
  • Route2
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0
    • null|null
      74-88-4
    • ~83%
    • In-stock
      1-Methyl-2,3-dihydro-1H-inden-1-ol|CS-0047056
      64666-42-8

    References

    • Oezdemirhan, Devrim; Sezer, Serdar; Soenmez, Yasemin Tetrahedron Asymmetry, 2008 , vol. 19, # 23 p. 2717 - 2720
  • Route3
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0
    • ~%
    • In-stock
      1-Methyl-2,3-dihydro-1H-inden-1-ol|CS-0047056
      64666-42-8

    References

    • Adam, Gerard; Andrieux, Jean; Plat, Michel M. Tetrahedron Letters, 1983 , vol. 24, # 34 p. 3609 - 3612

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.8403
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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