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CS-W001157 4
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Methyl2-amino-2-methyl-3-phenylpropanoatehydrochloride

  • CAS No. 64665-60-7

  • Cat. No. CS-0119892
  • Purity≥98%
  • MDL No.MFCD00237767

*For research and further manufacturing use only, not for direct human use.

Methyl2-amino-2-methyl-3-phenylpropanoatehydrochloride|CS-0119892

Structure of 64665-60-7

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General Information

  • CAS No. 64665-60-7
  • Cat. No. CS-0119892
  • Purity ≥98%
  • MDL No. MFCD00237767
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO₂
  • Molecular Weight 229.70
  • Synonym(s) Methyl 2-amino-2-methyl-3-phenylpropanoate hydrochloride
  • SMILES NC(CC1=CC=CC=C1)(C)C(OC)=O.[H]Cl

Description

Methyl 2-amino-2-methyl-3-phenylpropanoate hydrochloride features a chiral α-amino acid scaffold with a phenyl-substituted side chain, enabling direct incorporation into peptide synthesis. The hydrochloride salt enhances solubility and stability under standard handling conditions. This building block facilitates the construction of sterically hindered amino acid derivatives for medicinal chemistry applications.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      α-Methyl-DL-phenylalanine|CS-0201627
      1132-26-9
    • ~%
    • In-stock
      Methyl2-amino-2-methyl-3-phenylpropanoatehydrochloride|CS-0119892
      64665-60-7

    References

    • Huang, Ziwei; He, Ya-Bo; Raynor, Karen; Tallent, Melanie; Reisine, Terry; Goodman, Murray Journal of the American Chemical Society, 1992 , vol. 114, # 24 p. 9390 - 9401
  • Route2
    • null|null
      68870-85-9
    • null|null
      83575-33-1
    • ~%
    • In-stock
      Methyl2-amino-2-methyl-3-phenylpropanoatehydrochloride|CS-0119892
      64665-60-7

    References

    • Duhamel, Lucette; Duhamel, Pierre; Fouquay, Stephane; Eddine, Jamal Jamal; Peschard, Olivier; et al. Tetrahedron, 1988 , vol. 44, # 17 p. 5495 - 5506
  • Route3
    • null|null
      83575-33-1
    • null|null
      120238-43-9
    • ~%
    • In-stock
      Methyl2-amino-2-methyl-3-phenylpropanoatehydrochloride|CS-0119892
      64665-60-7

    References

    • Duhamel, Lucette; Duhamel, Pierre; Fouquay, Stephane; Eddine, Jamal Jamal; Peschard, Olivier; et al. Tetrahedron, 1988 , vol. 44, # 17 p. 5495 - 5506

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.5413
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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