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CS-W001157 4
Total: USD 88.00

7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate,97%(stabilized with HQ)

  • CAS No. 64630-63-3

  • Cat. No. CS-0160470
  • Purity96%(stabilized with HQ)
  • MDL No.MFCD28364662

*For research and further manufacturing use only, not for direct human use.

7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate,97%(stabilized with HQ)|CS-0160470

Structure of 64630-63-3

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General Information

  • CAS No. 64630-63-3
  • Cat. No. CS-0160470
  • Purity 96%(stabilized with HQ)
  • MDL No. MFCD28364662
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄O₃
  • Molecular Weight 182.22
  • Synonym(s) Acrylic Acid 7-Oxabicyclo[4.1.0]heptan-3-ylmethyl Ester (stabilized with HQ)
  • SMILES C=CC(OCC1CC2OC2CC1)=O

Description

7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate, 97% (stabilized with HQ) features a rigid bicyclic core that imparts unique stereochemical control in cycloaddition reactions. The acrylate ester group enables efficient conjugate addition and polymerization under mild conditions. This bench-stable reagent combines structural rigidity with reactive functionality, facilitating the synthesis of complex heterocycles and functionalized polymers.

Application

7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate, 97% (stabilized with HQ), serves as a versatile bicyclic Michael acceptor for conjugate additions in synthetic organic chemistry. Its strained oxabicyclic core enhances reactivity while maintaining bench stability due to hydroquinone stabilization. Functions effectively in nucleophilic ring-opening reactions and enables access to functionalized heterocyclic scaffolds via acrylate addition. Ideal for medicinal chemistry libraries and process development workflows requiring predictable, high-yielding transformations.

Synthesis

  • Route1
    • null|null
      79-21-0
    • null|null
      21367-02-2
    • ~%
    • In-stock
      7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate,97%(stabilized with HQ)|CS-0160470
      64630-63-3

    References

    • Frostick et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 3350,3352
  • Route2
    • null|null
      21367-02-2
    • ~%
    • In-stock
      7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate,97%(stabilized with HQ)|CS-0160470
      64630-63-3

    References

    • Batog, A. E.; Zaitsev, S. Yu.; Kiryushina, N. P.; Zaitseva, V. V. Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 76 - 79 Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 1 p. 90 - 94
  • Route3
    • null|null
      72581-32-9
    • ~%
    • In-stock
      7-Oxabicyclo[4.1.0]heptan-3-ylmethyl acrylate,97%(stabilized with HQ)|CS-0160470
      64630-63-3

    References

    • Batog, A. E.; Zaitsev, S. Yu.; Kiryushina, N. P.; Zaitseva, V. V. Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 76 - 79 Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 1 p. 90 - 94

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.83
  • LogP   1.2831
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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