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CS-W001157 4
Total: USD 88.00

3-Bromo-6-hydrazinylpyridazine

  • CAS No. 64461-67-2

  • Cat. No. CS-0169389
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Bromo-6-hydrazinylpyridazine|CS-0169389

Structure of 64461-67-2

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General Information

  • CAS No. 64461-67-2
  • Cat. No. CS-0169389
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅BrN₄
  • Molecular Weight 189.01
  • Synonym(s) 3-bromo-6-hydrazinepyridazine
  • SMILES NNC1=NN=C(Br)C=C1

Description

3-Bromo-6-hydrazinylpyridazine features a hydrazino group flanked by a bromine substituent on a pyridazine core, enabling selective coupling reactions. This electron-deficient heterocycle facilitates efficient functionalization in synthetic pathways, particularly in medicinal chemistry and bioconjugation applications. The molecule exhibits stability under standard conditions and integrates readily into complex architectures.

Application

3-Bromo-6-hydrazinylpyridazine serves as a versatile building block for constructing nitrogen-rich heterocycles, enabling direct coupling with electrophiles or transition-metal-catalyzed transformations. The hydrazinyl group facilitates cyclization reactions and acts as a key handle in the synthesis of pyrazolo- and triazolo-pyridazine scaffolds. Bench-stable and compatible with common protecting group strategies, it offers reliable functionality in medicinal chemistry campaigns targeting kinase inhibitors and other bioactive molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.83
  • LogP   0.5247
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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