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Structure of 64321-24-0
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2-Amino-6-chloronicotinamide features a chlorinated pyridine core with complementary amine and amide functionalities, enabling direct integration into bioactive scaffolds. This bench-stable derivative serves as a key building block for medicinal chemistry campaigns targeting kinase inhibitors and antiparasitic agents.
2-Amino-6-chloronicotinamide serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via coupling reactions and cyclization protocols. Its amino and amide functionalities provide orthogonal reactivity for sequential derivatization, while the chloro group offers a handle for palladium-catalyzed cross-coupling. The compound exhibits good bench stability and facilitates purification by standard chromatographic methods, making it well-suited for scalable API intermediate development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: