Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 2-amino-3-(4-fluorophenyl)propanoate hydrochloride

  • CAS No. 64282-12-8

  • Cat. No. CS-0097854
  • Purity≥97%
  • MDL No.MFCD00182718

*For research and further manufacturing use only, not for direct human use.

Methyl 2-amino-3-(4-fluorophenyl)propanoate hydrochloride|CS-0097854

Structure of 64282-12-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 64282-12-8
  • Cat. No. CS-0097854
  • Purity ≥97%
  • MDL No. MFCD00182718
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃ClFNO₂
  • Molecular Weight 233.67
  • Synonym(s) P-FLUORO-DL-PHENYLALANINE-OME HCL
  • SMILES O=C(C(CC1=CC=C(C=C1)F)N)OC.[H]Cl

Description

Methyl 2-amino-3-(4-fluorophenyl)propanoate hydrochloride delivers a stable, moisture-tolerant platform for synthesizing chiral intermediates in pharmaceutical development. The para-fluoro aryl group enhances metabolic stability, while the protonated amine ensures solubility and reactivity under standard conditions. This compound integrates readily into diverse coupling and cyclization workflows.

Application

Methyl 2-amino-3-(4-fluorophenyl)propanoate hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to chiral β-arylalanine derivatives. The protected amine and ester functionalities offer orthogonal reactivity, facilitating subsequent transformations such as amidation, reduction, or cyclization. Bench-stable and readily purified by recrystallization, it functions as a key intermediate in the synthesis of bioactive heterocycles and API scaffolds requiring fluorinated aromatic substitution.

Synthesis

  • Route1

    References

    • Kienzle, Gabriele J.; Reischl, Gerald; Machulla, H.-Juergen Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 4 p. 259 - 273

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.2903
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 64282-12-8 sigma64282-12-8 manufacturer64282-12-8 price64282-12-8 structure64282-12-8 SDSbuy 64282-12-864282-12-8 supplier64282-12-8 uses64282-12-8 molecular weightprice of 64282-12-864282-12-8 chemical name formula of 64282-12-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label