N-Methoxy-N,2,2-trimethylpropanamide

Name: N-Methoxy-N,2,2-trimethylpropanamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 64214-60-4
Cat. No. CS-0123045
Purity≥98%
MDL No.MFCD11847426

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-Methoxy-N,2,2-trimethylpropanamide|CS-0123045

Structure of 64214-60-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 64214-60-4
Cat. No. CS-0123045
Purity ≥98%
MDL No. MFCD11847426
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₅NO₂
Molecular Weight 145.20
Synonym(s) Propanamide, N-methoxy-N,2,2-trimethyl-
SMILES CC(C)(C)C(N(OC)C)=O

Description

N-Methoxy-N,2,2-trimethylpropanamide features a sterically hindered amide scaffold that enhances stability and facilitates selective reactivity in synthetic transformations. This bench-stable reagent integrates efficiently into coupling protocols, enabling reliable amide bond formation under standard conditions.

Application

N-Methoxy-N,2,2-trimethylpropanamide serves as a robust amide surrogate in synthetic workflows, enabling efficient formation of ketones via the modified Nef reaction. Its trimethyl-substituted backbone enhances bench stability and simplifies purification, while the methoxy group facilitates selective hydrolysis under mild conditions. This reagent functions effectively in the synthesis of carbonyl intermediates and provides excellent functional group tolerance in complex molecule assembly.

Synthesis

Route1
- In-stock
  
  6638-79-5
- 3282-30-2
- ~96%
- In-stock
  
  64214-60-4
References
- Kerr, William J.; Morrison, Angus J.; Pazicky, Marek; Weber, Tina Organic Letters, 2012 , vol. 14, # 9 p. 2250 - 2253
Route2
- 1117-97-1
- In-stock
  
  75-98-9
- ~73%
- In-stock
  
  64214-60-4
References
- Woo, Jacqueline C. S.; Fenster, Erik; Dake, Gregory R. Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8984 - 8986
Route3
- In-stock
  
  6638-79-5
- In-stock
  
  75-98-9
- ~82%
- In-stock
  
  64214-60-4
References
- Kim, Joong-Gon; Jang, Doo Ok Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 1 p. 171 - 173

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.54
LogP 1.0523
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Amide

Key Words

N-Methoxy-N,2,2-trimethylpropanamide sigmaN-Methoxy-N,2,2-trimethylpropanamide manufacturerN-Methoxy-N,2,2-trimethylpropanamide priceN-Methoxy-N,2,2-trimethylpropanamide structureN-Methoxy-N,2,2-trimethylpropanamide SDSbuy N-Methoxy-N,2,2-trimethylpropanamideN-Methoxy-N,2,2-trimethylpropanamide supplierN-Methoxy-N,2,2-trimethylpropanamide usesN-Methoxy-N,2,2-trimethylpropanamide molecular weightprice of N-Methoxy-N,2,2-trimethylpropanamideN-Methoxy-N,2,2-trimethylpropanamide chemical name formula of N-Methoxy-N,2,2-trimethylpropanamide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N-Methoxy-N,2,2-trimethylpropanamide

CAS No. 64214-60-4

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words