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CS-W001157 4
Total: USD 88.00

Antiarol

  • CAS No. 642-71-7

  • Cat. No. CS-W017005
  • Purity≥98%
  • MDL No.MFCD00008389

*For research and further manufacturing use only, not for direct human use.

Antiarol|CS-W017005

Structure of 642-71-7

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General Information

  • CAS No. 642-71-7
  • Cat. No. CS-W017005
  • Purity ≥98%
  • MDL No. MFCD00008389
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₄
  • Molecular Weight 184.19
  • Synonym(s) 3,4,5-Trimethoxyphenol
  • SMILES OC1=CC(OC)=C(OC)C(OC)=C1

Description

Antiarol is a bench-stable, moisture-tolerant reagent designed for efficient coupling reactions in synthetic organic chemistry. Featuring a reactive acylating moiety, it enables rapid amide bond formation under mild conditions. This robust functionality streamlines peptide and pharmaceutical intermediate synthesis without requiring stringent anhydrous handling.

Application

Antiarol serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of complex heterocyclic scaffolds. Its well-defined reactivity facilitates reliable coupling reactions and functional group transformations under standard conditions. The compound exhibits excellent bench stability and compatibility with common protecting groups, making it suitable for iterative synthesis workflows.

Synthesis

  • Route1

    References

    • Ten Brink; Vis; Arends; Sheldon Journal of Organic Chemistry, 2001 , vol. 66, # 7 p. 2429 - 2433
  • Route2
    • 2-(3,4,5-Trimethoxyphenyl)propan-2-ol|CS-1276489
      105205-66-1
    • ~87%
    • In-stock
      Antiarol|CS-W017005
      642-71-7

    References

    • Kabalka; Reddy; Narayana Tetrahedron Letters, 1993 , vol. 34, # 48 p. 7667 - 7668
  • Route3
    • null|null
      30225-76-4
    • ~%
    • In-stock
      Antiarol|CS-W017005
      642-71-7

    References

    • Narsaiah, A. Venkat; Nagaiah Synthesis, 2010 , # 16 art. no. Z07610SS, p. 2705 - 2707

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   47.92
  • LogP   1.418
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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