Tolbutamide

Name: Tolbutamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 64-77-7
Cat. No. CS-2500
Purity≥98%
MDL No.MFCD00027169

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HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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General Information
Application
Safety Information
Quality Control
Computational Chemistry Data

General Information

CAS No. 64-77-7
Cat. No. CS-2500
Purity ≥98%
MDL No. MFCD00027169
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₈N₂O₃S
Molecular Weight 270.35
Synonym(s) None
SMILES O=S(C1=CC=C(C)C=C1)(NC(NCCCC)=O)=O

Application

Tolbutamide serves as a well-established sulfonylurea scaffold for medicinal chemistry research, enabling the exploration of glucose-lowering mechanisms through targeted receptor binding. Its stable aryl sulfonamide core facilitates functional group modifications and offers predictable metabolic behavior, making it a reliable building block for developing antidiabetic agents.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 75.27
LogP 1.78302
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 5

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Tolbutamide

CAS No. 64-77-7