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CS-W001157 4
Total: USD 88.00

2-(4-Bromophenyl)pyridine

  • CAS No. 63996-36-1

  • Cat. No. CS-W003191
  • Purity≥97%
  • MDL No.MFCD04116231

*For research and further manufacturing use only, not for direct human use.

2-(4-Bromophenyl)pyridine|CS-W003191

Structure of 63996-36-1

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General Information

  • CAS No. 63996-36-1
  • Cat. No. CS-W003191
  • Purity ≥97%
  • MDL No. MFCD04116231
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈BrN
  • Molecular Weight 234.09
  • Synonym(s) Pyridine, 2-(4-broMophenyl)-2-(4-BroMophenyl)pyridine
  • SMILES Brc1ccc(cc1)c1ccccn1

Description

2-(4-Bromophenyl)pyridine features a brominated phenyl ring conjugated to a pyridine core, enabling robust coupling in cross-coupling reactions. This electron-deficient heteroaryl scaffold integrates readily into advanced materials and pharmaceutical intermediates. The bromine moiety offers high reactivity under palladium catalysis, while the planar structure supports strong π-stacking in functional molecular architectures.

Application

2-(4-Bromophenyl)pyridine serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its bromine substituent facilitates palladium- or nickel-mediated coupling with diverse nucleophiles, while the pyridine nitrogen offers coordination potential for catalyst systems. The compound exhibits excellent bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.5111
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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