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Structure of 6398-87-4
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3-(1,3-Dioxolan-2-yl)aniline features a protected hydroxyl-bearing dioxolane ring tethered to an aromatic amine, enabling stable storage and controlled release under acidic conditions. This masked phenol derivative integrates seamlessly into synthetic sequences requiring orthogonal functionality, offering enhanced handling without compromising reactivity in cross-coupling or cyclization workflows.
3-(1,3-Dioxolan-2-yl)aniline serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aromatic scaffolds. The 1,3-dioxolan-2-yl group acts as a stable, bench-compatible protecting group for aldehydes, readily cleaved under mild acidic conditions to reveal the corresponding aldehyde functionality. This enables downstream transformations such as reductive amination, coupling reactions, and heterocycle formation. Its compatibility with diverse reaction conditions and ease of purification make it particularly valuable in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: