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CS-W001157 4
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NMDA

  • CAS No. 6384-92-5

  • Cat. No. CS-2194
  • Purity≥98%
  • MDL No.MFCD00004226

*For research and further manufacturing use only, not for direct human use.

NMDA|CS-2194

Structure of 6384-92-5

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General Information

  • CAS No. 6384-92-5
  • Cat. No. CS-2194
  • Purity ≥98%
  • MDL No. MFCD00004226
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO₄
  • Molecular Weight 147.13
  • Synonym(s) N-Methyl-D-aspartic acid
  • SMILES O=C(O)C[C@H](C(O)=O)NC

Description

SPDP-type reagents have an amine-reactive N-hydroxysuccinimide (NHS) ester at one end and a suflhydryl-reactive 2-pyridyldithiol group at the opposite end. PEG4-SPDP has a 4-unit polyethylene glycol spacer arm, which confers greater solubility to the crosslinker and linked proteins compared to crosslinkers having only hydrocarbon spacers. Pyridyldithiol reagents produce disulfide-containing linkages that can be cleaved with reducing agents such as dithiothreitol (DTT). Crosslinking experiments with SPDP reagents are not limited to those involving proteins. Any of a variety of molecules with primary amines and sulfhydryl groups can be modified or crosslinked using an SPDP reagent.

Synthesis

  • Route1

    References

    • Helvetica Chimica Acta, , vol. 45, p. 2005 - 2011
  • Route2
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      144300-47-0
    • ~%
    • In-stock
      NMDA|CS-2194
      6384-92-5

    References

    • Helvetica Chimica Acta, , vol. 45, p. 2005 - 2011
  • Route3
    • null|null
      89464-62-0
    • ~%
    • In-stock
      NMDA|CS-2194
      6384-92-5

    References

    • Helvetica Chimica Acta, , vol. 45, p. 2005 - 2011

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   86.63
  • LogP   -0.8663
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   4

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