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Structure of 63810-78-6
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5-Bromo-4-chloro-2-(methylthio)pyrimidine is a halogenated pyrimidine derivative featuring complementary reactive sites for cross-coupling and functionalization. The methylthio group enhances solubility and electronic tuning, while the bromo and chloro substituents enable sequential derivatization under palladium catalysis. This compound serves as a key intermediate in medicinal chemistry and agrochemical synthesis, offering high reactivity with minimal side-product formation under standard conditions.
5-Bromo-4-chloro-2-(methylthio)pyrimidine serves as a versatile building block in heterocyclic synthesis, enabling selective functionalization via cross-coupling reactions. The bromo and chloro substituents provide orthogonal reactivity for palladium-catalyzed transformations, while the methylthio group offers mild oxidation stability and compatibility with standard protecting group strategies. This compound facilitates efficient access to substituted pyrimidines relevant to agrochemical and medicinal chemistry scaffolds.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2923
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Class : 8 (6.1)
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Packing Group : Ⅲ
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Hazard Statements : H301-H314-H318
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: