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CS-W001157 4
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N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride

  • CAS No. 6366-70-7

  • Cat. No. CS-W002176
  • Molecule weight406.90
  • Purity≥98%
  • MDL No.MFCD00038981

*For research and further manufacturing use only, not for direct human use.

N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride|CS-W002176

Structure of 6366-70-7

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General Information

  • CAS No. 6366-70-7
  • Cat. No. CS-W002176
  • Purity ≥98%
  • MDL No. MFCD00038981
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₇ClN₂O₄
  • Molecular Weight 406.90
  • Synonym(s) None
  • SMILES O=C(OCC1=CC=CC=C1)[C@@H](N)CCCCNC(OCC2=CC=CC=C2)=O.Cl

Description

N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride features a protected α-amino group and a reactive side-chain amine, enabling straightforward incorporation into peptide synthesis workflows. The carbobenzoxy (Cbz) group ensures stable Nα-protection, while the benzyl ester facilitates selective deprotection under mild hydrogenolysis conditions. This formulation combines robust stability with precise functional group handling for advanced synthetic applications.

Synthesis

  • Route1
    • null|null
      77236-13-6
    • ~93%
    • In-stock
      N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride|CS-W002176
      6366-70-7

    References

    • Kulikov, S. V.; Leonova, E. B.; Kalinina, N. M.; Samartsev, M. A.; Bubnova, L. N.; et al. Russian Journal of Bioorganic Chemistry, 1995 , vol. 21, # 6 p. 362 - 369 Bioorganicheskaya Khimiya, 1995 , vol. 21, # 6 p. 421 - 429
  • Route2

    References

    • US1312 H1, ;
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 48, # 13 p. 4285 - 4292

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   3.5756
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   10

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