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Structure of 635-79-0
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2-Methylquinoline-3-carboxylic acid features a fused quinoline core with a methyl group at the 2-position and a carboxylic acid at the 3-position, enabling direct integration into bioactive scaffolds. The electron-deficient quinoline ring enhances π-stacking interactions, while the carboxylic acid facilitates conjugation or salt formation. This compound serves as a key intermediate in medicinal chemistry for targeting kinase pathways and other protein-ligand interfaces.
2-Methylquinoline-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via standard coupling reactions. Its quinoline core provides enhanced metabolic stability and favorable pharmacokinetic properties, while the carboxylic acid group facilitates amide, ester, and heterocycle formation under mild conditions. Bench-stable and readily purified by recrystallization, it functions effectively in both small-molecule library synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: