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CS-W001157 4
Total: USD 88.00

Tetramethyl benzene-1,2,4,5-tetracarboxylate

  • CAS No. 635-10-9

  • Cat. No. CS-0145251
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tetramethyl benzene-1,2,4,5-tetracarboxylate|CS-0145251

Structure of 635-10-9

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General Information

  • CAS No. 635-10-9
  • Cat. No. CS-0145251
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₄O₈
  • Molecular Weight 310.26
  • Synonym(s) Tetramethyl pyromellitate
  • SMILES O=C(OC)C1=CC(C(OC)=O)=C(C(OC)=O)C=C1C(OC)=O

Description

Tetramethyl benzene-1,2,4,5-tetracarboxylate features four methyl ester groups arranged in a symmetric pattern on a benzene core, enabling efficient incorporation into high-performance polymers and conjugated materials. This electron-rich scaffold enhances solubility and thermal stability in synthetic applications.

Application

Tetramethyl benzene-1,2,4,5-tetracarboxylate serves as a versatile tetrasubstituted aromatic building block for the synthesis of complex heterocycles and functionalized arenes. Its four methyl ester groups enable sequential deprotection and coupling reactions under mild conditions, offering high functional group tolerance and excellent bench stability. The molecule facilitates efficient access to symmetric and asymmetric scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      292638-85-8
    • In-stock
      1,4-Dimethyl but-2-ynedioate|CS-D0471
      762-42-5
    • ~85%
    • In-stock
      Tetramethyl benzene-1,2,4,5-tetracarboxylate|CS-0145251
      635-10-9

    References

    • Zhou, Peng; Huang, Liangbin; Jiang, Huanfeng; Wang, Azhong; Li, Xianwei Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8279 - 8282
  • Route2
    • null|null
      828922-45-8
    • ~32%
    • In-stock
      Tetramethyl benzene-1,2,4,5-tetracarboxylate|CS-0145251
      635-10-9
    • null|null
      828922-46-9

    References

    • Tetrahedron Asymmetry, , vol. 15, # 23 p. 3805 - 3810
  • Route3
    • null|null
      18064-10-3
    • ~58%
    • In-stock
      Tetramethyl benzene-1,2,4,5-tetracarboxylate|CS-0145251
      635-10-9

    References

    • Wong Synthesis, 1984 , vol. NO. 9, p. 787 - 790

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   105.2
  • LogP   0.833
  • H_Acceptors   8
  • H_Donors   0
  • Rotatable_Bonds   4

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