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CS-W001157 4
Total: USD 88.00

6-(Hydroxymethyl)-1-methylpyridin-2(1H)-one

  • CAS No. 63487-00-3

  • Cat. No. CS-0149602
  • Molecule weight139.15
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-(Hydroxymethyl)-1-methylpyridin-2(1H)-one|CS-0149602

Structure of 63487-00-3

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General Information

  • CAS No. 63487-00-3
  • Cat. No. CS-0149602
  • Purity ≥98%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO₂
  • Molecular Weight 139.15
  • Synonym(s) 6-Hydroxymethyl-1-methyl-1H-pyridin-2-one
  • SMILES O=C1C=CC=C(CO)N1C

Description

6-(Hydroxymethyl)-1-methylpyridin-2(1H)-one features a pyridinone core with a strategically positioned hydroxymethyl group, enabling direct functionalization or conjugation in synthetic transformations. This bench-stable scaffold integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability for medicinal chemistry applications.

Application

6-(Hydroxymethyl)-1-methylpyridin-2(1H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct functionalization at the pyridone core. The hydroxymethyl group facilitates downstream derivatization via oxidation, substitution, or coupling reactions, while the 1-methylpyridin-2-one scaffold provides favorable solubility and metabolic stability. Its bench-stable nature and compatibility with standard purification methods make it well-suited for iterative synthesis workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   42.23
  • LogP   -0.1224
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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