Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Thiophene-2-sulfonamide

  • CAS No. 6339-87-3

  • Cat. No. CS-W002488
  • Purity≥97%
  • MDL No.MFCD00185853

*For research and further manufacturing use only, not for direct human use.

Thiophene-2-sulfonamide|CS-W002488

Structure of 6339-87-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 6339-87-3
  • Cat. No. CS-W002488
  • Purity ≥97%
  • MDL No. MFCD00185853
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅NO₂S₂
  • Molecular Weight 163.22
  • Synonym(s) Thiophene-α-sulfonamide
  • SMILES NS(=O)(=O)c1cccs1

Description

Thiophene-2-sulfonamide features a sulfur-containing heterocyclic core with a sulfonamide functional group, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, offering a robust platform for medicinal chemistry applications where electron-deficient aromatic systems are required.

Application

Thiophene-2-sulfonamide serves as a versatile building block in medicinal chemistry, offering a stable, bench-compatible scaffold for the synthesis of heterocyclic compounds. Its sulfonamide group provides strong hydrogen-bonding capacity and enhanced solubility, while the thiophene ring contributes π-conjugation and metabolic stability. The molecule participates reliably in Suzuki-Miyaura and Buchwald-Hartwig couplings, enabling efficient access to biologically active architectures.

Synthesis

  • Route1

    References

    • ISIS INNOVATION LIMITED; RUSSELL, Angela, Jane; SIM, Edith; DAVIES, Steven, Graham; WESTWOOD, Isaac, Mark; KAWAMURA, Akane; CRAWFORD, Matthew, Howard, James; LAURIERI, Nicola Patent: WO2011/55142 A2, 2011 ; Location in patent: Page/Page column 47 ; WO 2011/055142 A2
  • Route2

    References

    • Wan, Yiqian; Wu, Xiongyu; Kannan, Mahalingam A.; Alterman, Mathias Tetrahedron Letters, 2003 , vol. 44, # 24 p. 4523 - 4525
  • Route3
    • null|null
      75241-05-3
    • ~87%
    • In-stock
      Thiophene-2-sulfonamide|CS-W002488
      6339-87-3

    References

    • Obafemi, Craig. A.; Onigbinde, Adebayo O. Phosphorus, Sulfur and Silicon and the Related Elements, 1991 , vol. 57, # 1/2 p. 75 - 81

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.16
  • LogP   0.3955
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Thiophene-2-sulfonamide sigmaThiophene-2-sulfonamide manufacturerThiophene-2-sulfonamide priceThiophene-2-sulfonamide structureThiophene-2-sulfonamide SDSbuy Thiophene-2-sulfonamideThiophene-2-sulfonamide supplierThiophene-2-sulfonamide usesThiophene-2-sulfonamide molecular weightprice of Thiophene-2-sulfonamideThiophene-2-sulfonamide chemical name formula of Thiophene-2-sulfonamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label