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CS-W001157 4
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2-(7-Bromo-1H-indol-3-yl)acetic acid

  • CAS No. 63352-97-6

  • Cat. No. CS-0186433
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(7-Bromo-1H-indol-3-yl)acetic acid|CS-0186433

Structure of 63352-97-6

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General Information

  • CAS No. 63352-97-6
  • Cat. No. CS-0186433
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrNO₂
  • Molecular Weight 254.08
  • Synonym(s) 1H-Indole-3-aceticacid,7-bromo-(9CI)
  • SMILES O=C(O)CC1=CNC2=C1C=CC=C2Br

Description

This indole-acetic acid derivative features a brominated indole core linked to a carboxylic acid side chain, enabling direct integration into bioconjugation and medicinal chemistry workflows. The electron-deficient bromo substituent enhances reactivity in cross-coupling reactions, while the pendant acid group offers versatile derivatization potential for peptide and polymer conjugates under standard conditions.

Application

2-(7-Bromo-1H-indol-3-yl)acetic acid serves as a versatile building block for indole-based bioactive molecules, enabling efficient access to pharmaceutically relevant scaffolds. The bromo substituent facilitates palladium-catalyzed cross-coupling reactions, while the carboxylic acid group supports direct derivatization or incorporation into peptide-like systems. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for medicinal chemistry campaigns and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   53.09
  • LogP   2.5575
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   2

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