Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-(Pyridin-4-yl)propanoic acid

  • CAS No. 6318-43-0

  • Cat. No. CS-0140245
  • Purity≥96%
  • MDL No.MFCD00084846

*For research and further manufacturing use only, not for direct human use.

3-(Pyridin-4-yl)propanoic acid|CS-0140245

Structure of 6318-43-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 6318-43-0
  • Cat. No. CS-0140245
  • Purity ≥96%
  • MDL No. MFCD00084846
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) 3-(4-PYRIDYL)PROPANOIC ACID
  • SMILES O=C(O)CCC1=CC=NC=C1

Description

This pyridine-functionalized carboxylic acid integrates a conjugated aliphatic chain, enabling versatile coupling reactions in synthetic organic chemistry. The para-pyridyl group provides a robust anchor for metal coordination and hydrogen bonding, while the terminal carboxylic acid facilitates efficient derivatization under standard conditions.

Application

3-(Pyridin-4-yl)propanoic acid serves as a versatile building block for medicinal chemistry and materials science, enabling efficient construction of bioactive heterocyclic scaffolds. Its conjugated pyridine–alkyl chain facilitates robust coupling reactions and enhances metabolic stability in drug candidates. The carboxylic acid group provides a handle for derivatization via amide, ester, or amidation protocols, while the pyridine moiety offers favorable solubility and π-stacking interactions. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.

Synthesis

  • Route1

    References

    • MERCK and CO., INC. Patent: WO2004/58702 A2, 2004 ; Location in patent: Page 46; 27 ; WO 2004/058702 A2
  • Route2
    • Ethyl 3-(pyridin-4-yl)propanoate|CS-0365730
      52809-19-5
    • ~72%
    • In-stock
      3-(Pyridin-4-yl)propanoic acid|CS-0140245
      6318-43-0

    References

    • Block, Michael Howard; Donald, Craig Samuel; Brittain, David Robert; Foote, Kevin Michael Patent: US2003/225097 A1, 2003 ; Location in patent: Page 51 ;
  • Route3

    References

    • Merck and Co., Inc. Patent: US6642237 B1, 2003 ; Location in patent: Page/Page column 131-132 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.0988
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-(Pyridin-4-yl)propanoic acid sigma3-(Pyridin-4-yl)propanoic acid manufacturer3-(Pyridin-4-yl)propanoic acid price3-(Pyridin-4-yl)propanoic acid structure3-(Pyridin-4-yl)propanoic acid SDSbuy 3-(Pyridin-4-yl)propanoic acid3-(Pyridin-4-yl)propanoic acid supplier3-(Pyridin-4-yl)propanoic acid uses3-(Pyridin-4-yl)propanoic acid molecular weightprice of 3-(Pyridin-4-yl)propanoic acid3-(Pyridin-4-yl)propanoic acid chemical name formula of 3-(Pyridin-4-yl)propanoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label