(R)-4-Propyldihydrofuran-2(3H)-one

Name: (R)-4-Propyldihydrofuran-2(3H)-one
Brand: ChemScene
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CAS No. 63095-51-2
Cat. No. CS-0090076
Purity≥97%
MDL No.MFCD29905061

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-4-Propyldihydrofuran-2(3H)-one|CS-0090076

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General Information

CAS No. 63095-51-2
Cat. No. CS-0090076
Purity ≥97%
MDL No. MFCD29905061
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₂O₂
Molecular Weight 128.17
Synonym(s) brivaracetam intermediate 1
SMILES O=C1OC[C@H](CCC)C1

Description

(R)-4-Propyldihydrofuran-2(3H)-one is a chiral heterocyclic building block featuring a saturated γ-lactone core with defined stereochemistry at the 4-position. This bench-stable, moisture-tolerant scaffold integrates readily into complex molecular architectures, enabling precise control over spatial orientation in asymmetric synthesis and medicinal chemistry applications.

Application

(R)-4-Propyldihydrofuran-2(3H)-one serves as a versatile chiral building block in medicinal chemistry, enabling stereoselective synthesis of bioactive molecules. Its saturated γ-lactone core exhibits bench stability and compatibility with common functional groups, facilitating downstream transformations such as reduction, nucleophilic addition, and cross-coupling. The defined (R)-stereochemistry supports consistent stereochemical outcomes in asymmetric synthesis workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

TPSA 26.3
LogP 1.3496
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Key Words

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(R)-4-Propyldihydrofuran-2(3H)-one

CAS No. 63095-51-2

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