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CS-W001157 4
Total: USD 88.00

2,4-Dichlorophenylacetonitrile

  • CAS No. 6306-60-1

  • Cat. No. CS-0071560
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,4-Dichlorophenylacetonitrile|CS-0071560

Structure of 6306-60-1

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General Information

  • CAS No. 6306-60-1
  • Cat. No. CS-0071560
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅Cl₂N
  • Molecular Weight 186.04
  • Synonym(s) 2,4-Dichlorobenzyl cyanide
  • SMILES N#CCC1=C(Cl)C=C(Cl)C=C1

Description

2,4-Dichlorophenylacetonitrile was used in the synthesis of 2,4-dichloromandelic acid.

Application

2,4-Dichlorophenylacetonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis. Its electron-withdrawing dichlorophenyl group enhances nitrile reactivity, enabling efficient transformations into carboxylic acids, amides, and heterocycles. The compound exhibits excellent bench stability, facilitates straightforward purification via recrystallization or chromatography, and demonstrates broad functional group tolerance in standard coupling and cyclization protocols.

Synthesis

  • Route1
    • null|null
      773837-37-9
    • null|null
      94-99-5
    • ~84%
    • In-stock
      2,4-Dichlorophenylacetonitrile|CS-0071560
      6306-60-1

    References

    • Organic Preparations and Procedures International, , vol. 43, # 3 p. 285 - 291
  • Route2

    References

    • Tetrahedron Letters, , vol. 49, # 5 p. 914 - 918
  • Route3
    • null|null
      877468-98-9
    • null|null
      10442-39-4
    • ~88%
    • In-stock
      2,4-Dichlorophenylacetonitrile|CS-0071560
      6306-60-1

    References

    • Comptes Rendus Chimie, , vol. 13, # 12 p. 1468 - 1473

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.79
  • LogP   3.05948
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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