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CS-W001157 4
Total: USD 88.00

(4-Pyridyl)acetone

  • CAS No. 6304-16-1

  • Cat. No. CS-W002401
  • Purity≥96%
  • MDL No.MFCD00129043

*For research and further manufacturing use only, not for direct human use.

(4-Pyridyl)acetone|CS-W002401

Structure of 6304-16-1

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General Information

  • CAS No. 6304-16-1
  • Cat. No. CS-W002401
  • Purity ≥96%
  • MDL No. MFCD00129043
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO
  • Molecular Weight None
  • Synonym(s) 4-Acetonylpyridine
  • SMILES CC(CC1=CC=NC=C1)=O

Description

(4-Pyridyl)acetone features a pyridyl ring conjugated to an acetyl group, enabling versatile coupling reactions in synthetic chemistry. This bench-stable compound integrates readily into heterocyclic frameworks and serves as a key intermediate for pharmaceuticals and functional materials.

Application

(4-Pyridyl)acetone serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and functionalized aromatic systems. Its pyridyl moiety provides a robust site for metal-catalyzed coupling reactions, while the acetyl group facilitates nucleophilic addition, condensation, and oxidation to carboxylic acid derivatives. The compound exhibits good bench stability and compatibility with common protecting groups, making it suitable for iterative synthesis strategies in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      216529-28-1
    • ~34%
    • In-stock
      (4-Pyridyl)acetone|CS-W002401
      6304-16-1
    • null|null
      216504-21-1

    References

    • US6423713 B1, ; US 6423713 B1
  • Route2
    • null|null
      93617-62-0
    • ~70%
    • In-stock
      (4-Pyridyl)acetone|CS-W002401
      6304-16-1

    References

    • Tetrahedron Letters, , vol. 25, # 31 p. 3297 - 3300
  • Route3
    • null|null
      108-89-4
    • null|null
      75-36-5
    • ~%
    • In-stock
      (4-Pyridyl)acetone|CS-W002401
      6304-16-1

    References

    • US4681944 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS05
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.2131
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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