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CS-W001157 4
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2-(Pyridin-3-yl)ethan-1-ol

  • CAS No. 6293-56-7

  • Cat. No. CS-0139429
  • Purity≥96%
  • MDL No.MFCD00831047

*For research and further manufacturing use only, not for direct human use.

2-(Pyridin-3-yl)ethan-1-ol|CS-0139429

Structure of 6293-56-7

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General Information

  • CAS No. 6293-56-7
  • Cat. No. CS-0139429
  • Purity ≥96%
  • MDL No. MFCD00831047
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO
  • Molecular Weight 123.16
  • Synonym(s) None
  • SMILES OCCC1=CC=CN=C1

Description

2-(Pyridin-3-yl)ethan-1-ol features a pyridin-3-yl group linked to a hydroxyethyl side chain, combining nitrogen heterocycle reactivity with a polar alcohol functionality. This structure enables versatile integration into synthetic scaffolds requiring both hydrogen bonding capacity and π-interaction potential. The molecule exhibits good solubility in common organic solvents and stability under standard bench conditions, facilitating its use in medicinal chemistry and materials development workflows.

Application

2-(Pyridin-3-yl)ethan-1-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-containing scaffolds through standard functional group transformations. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward derivatization, including oxidation to the corresponding aldehyde or esterification for downstream coupling applications.

Synthesis

  • Route1

    References

    • Das, Shoubhik; Moeller, Konstanze; Junge, Kathrin; Beller, Matthias Chemistry - A European Journal, 2011 , vol. 17, # 27 p. 7414 - 7417
  • Route2

    References

    • Lowen, Gregory T.; Almond, Merrick R.; Rideout, Janet L. Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 6 p. 1663 - 1665
  • Route3
    • 3-Pyridylacetic acid hydrochloride Risedronate  Impurity|CS-0229121
      6419-36-9
    • ~96%
    • In-stock
      2-(Pyridin-3-yl)ethan-1-ol|CS-0139429
      6293-56-7

    References

    • Eisai Co., Ltd. Patent: US2002/19531 A1, 2002 ; US 20020019531 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   0.6164
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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