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CS-W001157 4
Total: USD 88.00

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate

  • CAS No. 6283-74-5

  • Cat. No. CS-W014861
  • Purity≥95%
  • MDL No.MFCD00037918

*For research and further manufacturing use only, not for direct human use.

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate|CS-W014861

Structure of 6283-74-5

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General Information

  • CAS No. 6283-74-5
  • Cat. No. CS-W014861
  • Purity ≥95%
  • MDL No. MFCD00037918
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₇
  • Molecular Weight 216.15
  • Synonym(s) diacetyl-L-tartaric anhydride
  • SMILES O=C1[C@H](OC(C)=O)[C@@H](OC(C)=O)C(O1)=O

Description

(+)-O,O-Diacetyl-L-tartaric anhydride is an HPLC derivatization reagent for UV/Vis detection. It is mainly employed as a reagent for the chiral derivatization of amino alcohols. It also reacts with alkanoamines in aprotic medium containing trichloroacetic acid and produces tartaric acid monoesters.(+)-O,O-Diacetyl-L-tartaric anhydride may be used as a chiral derivatizating agent in the following:determination of enantiomeric vigabatrin in mouse serum samples using ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UHPLC-Q-TOF-M)determination of trantinterol in rat plasma by ultra performance liquid chromatographyelectrospray ionization mass spectrometry (UPLCMS/MS)

Synthesis

  • Route1
    • null|null
      87-69-4
    • null|null
      108-24-7
    • ~94%
    • In-stock
      (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate|CS-W014861
      6283-74-5

    References

    • Mravik, Andras; Boecskei, Zsolt; Keszei, Sandor; Elekes, Ferenc; Fogassy, Elemer Tetrahedron Asymmetry, 1996 , vol. 7, # 5 p. 1477 - 1484
  • Route2
    • null|null
      108-24-7
    • null|null
      87-69-4
    • ~78%
    • In-stock
      (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate|CS-W014861
      6283-74-5

    References

    • Huang, Huiming; Chen, Dan; Li, Shaohua; Liu, Chengmei Letters in Organic Chemistry, 2010 , vol. 7, # 2 p. 155 - 158
  • Route3
    • In-stock
      D-Tartaric acid|CS-0017144
      147-71-7
    • null|null
      108-24-7
    • ~71%
    • In-stock
      (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate|CS-W014861
      6283-74-5

    References

    • Dobashi, Yasuo; Hara, Shoji Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2490 - 2496

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   95.97
  • LogP   -1.0668
  • H_Acceptors   7
  • H_Donors   0
  • Rotatable_Bonds   2

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