Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Chloro-2-nitrobenzoic acid

  • CAS No. 6280-88-2

  • Cat. No. CS-W015545
  • Purity≥98%
  • MDL No.MFCD00007214

*For research and further manufacturing use only, not for direct human use.

4-Chloro-2-nitrobenzoic acid|CS-W015545

Structure of 6280-88-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 6280-88-2
  • Cat. No. CS-W015545
  • Purity ≥98%
  • MDL No. MFCD00007214
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClNO₄
  • Molecular Weight 201.56
  • Synonym(s) 4-chloro-2-nitrobenzoate
  • SMILES O=C(O)C1=CC=C(Cl)C=C1[N+]([O-])=O

Description

4-Chloro-2-nitrobenzoic acid features a chlorine substituent and a nitro group positioned ortho to the carboxylic acid, creating a highly electron-deficient aromatic system. This combination enhances reactivity in coupling reactions and facilitates direct functionalization under mild conditions. The compound serves as a key building block for pharmaceutical intermediates and specialty dyes.

Application

4-Chloro-2-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other heterocyclic scaffolds. The ortho-nitro group facilitates directed metalation and subsequent functionalization, while the carboxylic acid enables amide coupling and salt formation. Its bench-stable crystalline form simplifies handling and purification, supporting scalable transformations in multi-step syntheses.

Synthesis

  • Route1

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 37, p. 197
  • Route2
    • null|null
      89-63-4
    • ~%
    • In-stock
      4-Chloro-2-nitrobenzoic acid|CS-W015545
      6280-88-2

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 37, p. 197
  • Route3
    • null|null
      89-59-8
    • ~%
    • In-stock
      4-Chloro-2-nitrobenzoic acid|CS-W015545
      6280-88-2

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 36, p. 22 Chemische Berichte, , vol. 24, p. 3814 Monatshefte fuer Chemie, , vol. 22, p. 474 Journal of the Chemical Society, , vol. 87, p. 1271

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   80.44
  • LogP   1.9464
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Chloro-2-nitrobenzoic acid sigma4-Chloro-2-nitrobenzoic acid manufacturer4-Chloro-2-nitrobenzoic acid price4-Chloro-2-nitrobenzoic acid structure4-Chloro-2-nitrobenzoic acid SDSbuy 4-Chloro-2-nitrobenzoic acid4-Chloro-2-nitrobenzoic acid supplier4-Chloro-2-nitrobenzoic acid uses4-Chloro-2-nitrobenzoic acid molecular weightprice of 4-Chloro-2-nitrobenzoic acid4-Chloro-2-nitrobenzoic acid chemical name formula of 4-Chloro-2-nitrobenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label