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Structure of 6270-63-9
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2-Hydroxypyrazine features a pyrazine core with a hydroxyl group at the 2-position, delivering enhanced polarity and hydrogen-bonding capacity. This configuration supports integration into bioactive scaffolds and enables directed functionalization in synthetic pathways. The compound exhibits bench-stable behavior under standard conditions and serves as a key intermediate in heterocyclic chemistry.
2-Hydroxypyrazine serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the pyrazine core through electrophilic substitution or metal-catalyzed coupling. Its hydroxyl group facilitates derivatization via esterification, etherification, or transition-metal-mediated cross-coupling reactions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthetic sequences in medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: