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CS-W001157 4
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Potassium 2,6-dibromo-4-((3,5-dibromo-4-oxocyclohexa-2,5-dien-1-ylidene)(2-(ethoxycarbonyl)phenyl)methyl)phenolate

  • CAS No. 62637-91-6

  • Cat. No. CS-0128731
  • Molecule weight700.05
  • Purity≥97%
  • MDL No.MFCD00011662

*For research and further manufacturing use only, not for direct human use.

Potassium 2,6-dibromo-4-((3,5-dibromo-4-oxocyclohexa-2,5-dien-1-ylidene)(2-(ethoxycarbonyl)phenyl)methyl)phenolate|CS-0128731

Structure of 62637-91-6

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General Information

  • CAS No. 62637-91-6
  • Cat. No. CS-0128731
  • Purity ≥97%
  • MDL No. MFCD00011662
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₁₃Br₄KO₄
  • Molecular Weight 700.05
  • Synonym(s) Tetrabromophenolphthalein ethyl ester, potassium salt
  • SMILES O=C(OCC)C1=CC=CC=C1/C(C2=CC(Br)=C([O-])C(Br)=C2)=C3C=C(Br)C(C(Br)=C/3)=O.[K+]

Description

Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd?= 1011?vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   66.43
  • LogP   3.4081
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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