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CS-W001157 4
Total: USD 88.00

Pent-2-yn-1-ol

  • CAS No. 6261-22-9

  • Cat. No. CS-0143646
  • Purity≥96%
  • MDL No.MFCD00040915

*For research and further manufacturing use only, not for direct human use.

Pent-2-yn-1-ol|CS-0143646

Structure of 6261-22-9

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General Information

  • CAS No. 6261-22-9
  • Cat. No. CS-0143646
  • Purity ≥96%
  • MDL No. MFCD00040915
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O
  • Molecular Weight 84.12
  • Synonym(s) 2-Pentyn-1-ol
  • SMILES CCC#CCO

Description

2-Pentyn-1-ol was employed as starting reagent for the synthesis of (-)-muricatacin. It was also used in the preparation of (2Z)-3-tributylstannyl-2-penten-1-ol.

Application

Pent-2-yn-1-ol serves as a versatile synthetic building block featuring a terminal alkyne and primary alcohol functional group. Its reactivity enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for triazole formation, and the hydroxyl group facilitates protection, derivatization, or metal-catalyzed coupling reactions. The molecule exhibits good bench stability and is readily purified by distillation or chromatography, making it well-suited for use in medicinal chemistry, materials science, and modular synthesis workflows.

Synthesis

  • Route1
    • null|null
      6261-21-8
    • ~94%
    • In-stock
      Pent-2-yn-1-ol|CS-0143646
      6261-22-9

    References

    • Fadel, A.; Salaun, J. Tetrahedron, 1985 , vol. 41, # 7 p. 1267 - 1276
  • Route2
    • null|null
      50-00-0
    • null|null
      107-00-6
    • ~87%
    • In-stock
      Pent-2-yn-1-ol|CS-0143646
      6261-22-9

    References

    • RETROTOPE, INC. Patent: US2011/105609 A1, 2011 ; Location in patent: Page/Page column 19 ;
  • Route3
    • null|null
      109-72-8
    • null|null
      107-00-6
    • ~98%
    • In-stock
      Pent-2-yn-1-ol|CS-0143646
      6261-22-9

    References

    • CHON Corporation Patent: US4143230 A1, 1979 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1987
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   0.3921
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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