Lot numbers can be found on the outside label of a product:
L-Homocystine
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CAS No. 626-72-2
- Cat. No. CS-W012406
- Purity≥95%
- MDL No.MFCD00020391
*For research and further manufacturing use only, not for direct human use.
Structure of 626-72-2
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General Information
- CAS No. 626-72-2
- Cat. No. CS-W012406
- Purity ≥95%
- MDL No. MFCD00020391
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₁₆N₂O₄S₂
- Molecular Weight 268.35
- Synonym(s) None
- SMILES OC([C@@H](N)CCSSCC[C@H](N)C(O)=O)=O
Description
L-Homocystine features a disulfide-bridged cysteine dimer with a unique α,ω-diamino acid backbone, enabling selective bioconjugation and protein crosslinking. This bench-stable, moisture-tolerant reagent integrates readily into peptide synthesis workflows, offering reliable sulfur-directed functionalization in chemical biology applications.
Application
L-Homocystine serves as a key sulfur-containing amino acid building block for the synthesis of biologically relevant thiol-containing peptides and thioether-linked scaffolds. Its disulfide functionality enables controlled redox chemistry in peptide conjugation and protein engineering workflows. The compound exhibits sufficient bench stability for routine handling and facilitates efficient incorporation into complex molecular architectures via standard coupling protocols.
Synthesis
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Route1
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In-stock
6027-13-0 - ~94%
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In-stock
626-72-2
References
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Miyazaki, Hideya; Ohta, Atsushi; Kawakatsu, Nobuyuki; Waki, Yukitaka; Gogun, Yasuhiro; et al. Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 2 p. 536 - 540
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Route2
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7689-60-3 - ~%
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In-stock
626-72-2
References
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Biochemical Preparations, , vol. 5, p. 96 Journal of Biological Chemistry, , vol. 109, p. 97,101
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References
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Journal of Organic Chemistry, , vol. 57, # 1 p. 123 - 127
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Safety Information
Download SDS|
GHS Pictogram :
N/A
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GHS No : N/A
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Signal Word : N/A
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : N/A
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Precautionary Statements : N/A
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Quality Control
Computational Chemistry Data
- TPSA 126.64
- LogP -0.0282
- H_Acceptors 6
- H_Donors 4
- Rotatable_Bonds 9
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