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CS-W001157 4
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3-Bromopyridine

  • CAS No. 626-55-1

  • Cat. No. CS-0008362
  • Purity≥98%
  • MDL No.MFCD00006373

*For research and further manufacturing use only, not for direct human use.

3-Bromopyridine|CS-0008362

Structure of 626-55-1

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General Information

  • CAS No. 626-55-1
  • Cat. No. CS-0008362
  • Purity ≥98%
  • MDL No. MFCD00006373
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrN
  • Molecular Weight 158.00
  • Synonym(s) 3-Pyridyl bromide; 3-Bromopyridine
  • SMILES BrC1=CC=CN=C1

Description

3-Bromopyridine is a bench-stable, moisture-tolerant heterocycle featuring a bromine atom at the meta position relative to the nitrogen. This substitution pattern enables selective cross-coupling reactions in late-stage functionalization, particularly under palladium catalysis. The electron-deficient pyridine ring enhances reactivity in nucleophilic displacement and facilitates coupling with arylboron reagents. Its compatibility with diverse reaction conditions makes it a reliable building block for pharmaceutical intermediates and agrochemicals.

Application

3-Bromopyridine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its bromine substituent provides high reactivity under standard conditions while maintaining bench stability and compatibility with diverse functional groups. The pyridine core offers orthogonal reactivity for further derivatization, making it a practical scaffold for pharmaceutical intermediates and agrochemicals.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   1.8441
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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