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CS-W001157 4
Total: USD 88.00

1,3-Phenylenedimethanol

  • CAS No. 626-18-6

  • Cat. No. CS-0128756
  • Purity≥95%
  • MDL No.MFCD00004649

*For research and further manufacturing use only, not for direct human use.

1,3-Phenylenedimethanol|CS-0128756

Structure of 626-18-6

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General Information

  • CAS No. 626-18-6
  • Cat. No. CS-0128756
  • Purity ≥95%
  • MDL No. MFCD00004649
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O₂
  • Molecular Weight 138.16
  • Synonym(s) α,α'-Dihydroxy-m-xylene
  • SMILES OCC1=CC=CC(CO)=C1

Description

1,3-Benzenedimethanol was used in the synthesis of a series of cross-linked poly(orthocarbonate)s. It was also used in the synthesis of mixed-tethered system, required for the preparation of e-edge-[60]fullerenylmethanodihydropyrrole adduct.

Application

1,3-Phenylenedimethanol serves as a versatile diol building block for the synthesis of functionalized aromatic compounds and heterocyclic scaffolds. Its bench-stable, crystalline nature and orthogonal reactivity enable efficient protection/deprotection strategies and selective transformations in multistep syntheses. The molecule functions effectively in coupling reactions and as a precursor to polyfunctionalized arenes used in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • Chemistry - A European Journal, , vol. 19, # 24 p. 7701 - 7707
  • Route2

    References

    • EP2657214 A1, ; Paragraph 0030; 0043-0044 ;
  • Route3

    References

    • Bioorganic and Medicinal Chemistry, , vol. 17, # 5 p. 1974 - 1981

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P330-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.6712
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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