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Structure of 626-13-1
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Di-m-tolylamine features a symmetric bis(ortho-tolyl) structure that imparts enhanced steric protection and electronic stabilization. This bench-stable compound serves as a robust scaffold in cross-coupling reactions and transition-metal catalysis, where its electron-rich aryl groups facilitate oxidative addition and ligand exchange.
Di-m-tolylamine serves as a stable, bench-ready aryl amine scaffold for constructing biaryl systems and heterocyclic frameworks. Its ortho-methyl substituents enhance steric shielding and oxidative stability, enabling reliable coupling reactions with palladium catalysts. The molecule functions effectively in Suzuki-Miyaura, Buchwald-Hartwig, and nitration protocols, offering predictable regiochemistry and straightforward purification via crystallization or column chromatography.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: