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CS-W001157 4
Total: USD 88.00

Captopril

  • CAS No. 62571-86-2

  • Cat. No. CS-2425
  • Purity≥98%
  • MDL No.MFCD00168073

*For research and further manufacturing use only, not for direct human use.

Captopril|CS-2425

Structure of 62571-86-2

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General Information

  • CAS No. 62571-86-2
  • Cat. No. CS-2425
  • Purity ≥98%
  • MDL No. MFCD00168073
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅NO₃S
  • Molecular Weight 217.29
  • Synonym(s) SQ 14225
  • SMILES O=C(O)[C@H]1N(C([C@H](C)CS)=O)CCC1

Application

Captopril serves as a well-established angiotensin-converting enzyme (ACE) inhibitor, featuring a thiol-containing functional group that enables direct interaction with the catalytic zinc ion in ACE. Its structure facilitates potent inhibition of vasoconstrictive peptide formation, making it a foundational scaffold in cardiovascular therapeutics. The molecule exhibits bench-stable handling and is widely used in medicinal chemistry research for validating ACE-targeted assays and developing analogs with improved pharmacokinetic profiles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H341-H360
Precautionary Statements : P201-P202-P261-P272-P280-P302+P352-P308+P313-P333+P317-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.61
  • LogP   0.6279
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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