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Structure of 625-56-9
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Chloromethyl acetate is a reactive acylating agent featuring a chloromethyl group attached to an ester moiety. This compound facilitates efficient alkylation under mild conditions, enabling direct functionalization of nucleophiles without requiring strong bases. The molecule exhibits high reactivity toward amines and thiols, delivering stable ether and thioether products. Its moderate stability under standard handling allows for controlled reaction kinetics in synthetic workflows.
Chloromethyl acetate serves as a versatile acetylating and chloromethylating agent, enabling efficient introduction of both acetyl and chloromethyl groups in sequential or one-pot transformations. Its bench-stable liquid form facilitates handling, while broad functional group tolerance supports use in complex molecule synthesis. Functions effectively in nucleophilic substitution reactions, particularly for preparing acetate-protected intermediates or generating reactive alkylating species under mild conditions.
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GHS Pictogram :
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GHS No : GHS02,GHS05,GHS07
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅱ
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Hazard Statements : H225-H314-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P261-P264-P271-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: