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CS-W001157 4
Total: USD 88.00

6-Chloroquinoline-4-carboxylic acid

  • CAS No. 62482-29-5

  • Cat. No. CS-0139267
  • Purity≥95%
  • MDL No.MFCD07506540
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Chloroquinoline-4-carboxylic acid|CS-0139267

Structure of 62482-29-5

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Description

6-Chloroquinoline-4-carboxylic acid features a chlorine substituent at the 6-position and a carboxylic acid group at the 4-position of the quinoline core. This electron-deficient heterocycle integrates readily into synthetic routes requiring polar, planar scaffolds. The compound serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and fluorescent probes, leveraging its ability to participate in amidation and coupling reactions under standard conditions.

Application

6-Chloroquinoline-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position via coupling reactions. The carboxylic acid group facilitates amide and ester formation, while the chlorine substituent provides a handle for palladium-catalyzed cross-coupling. Its stability under standard reaction conditions and compatibility with diverse transformations make it well-suited for constructing quinoline-based pharmacophores and API intermediates.

General Information

  • CAS No. 62482-29-5
  • Cat. No. CS-0139267
  • Purity ≥95%
  • MDL No. MFCD07506540
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆ClNO₂
  • Molecular Weight 207.61
  • Synonym(s) 6-CHLORO-QUINOLINE-4-CARBOXYLIC ACID
  • SMILES O=C(C1=CC=NC2=CC=C(Cl)C=C12)O

Computational Chemistry Data

  • TPSA   50.19
  • LogP   2.5864
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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