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Structure of 62482-29-5
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6-Chloroquinoline-4-carboxylic acid features a chlorine substituent at the 6-position and a carboxylic acid group at the 4-position of the quinoline core. This electron-deficient heterocycle integrates readily into synthetic routes requiring polar, planar scaffolds. The compound serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and fluorescent probes, leveraging its ability to participate in amidation and coupling reactions under standard conditions.
6-Chloroquinoline-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position via coupling reactions. The carboxylic acid group facilitates amide and ester formation, while the chlorine substituent provides a handle for palladium-catalyzed cross-coupling. Its stability under standard reaction conditions and compatibility with diverse transformations make it well-suited for constructing quinoline-based pharmacophores and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: