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CS-W001157 4
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Oxetan-3-ylmethanamine

  • CAS No. 6246-05-5

  • Cat. No. CS-W008698
  • Purity≥97%
  • MDL No.MFCD12547197

*For research and further manufacturing use only, not for direct human use.

Oxetan-3-ylmethanamine|CS-W008698

Structure of 6246-05-5

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General Information

  • CAS No. 6246-05-5
  • Cat. No. CS-W008698
  • Purity ≥97%
  • MDL No. MFCD12547197
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO
  • Molecular Weight 87.12
  • Synonym(s) 3-Oxetanemethanamine
  • SMILES NCC1COC1

Description

Oxetan-3-ylmethanamine features a strained oxetane ring fused to a primary amine, delivering high reactivity in bioconjugation and medicinal chemistry. This bench-stable, moisture-tolerant building block integrates readily into peptide and small-molecule architectures, enabling efficient coupling under mild conditions.

Application

Oxetan-3-ylmethanamine serves as a valuable building block in medicinal chemistry, enabling the incorporation of a strained oxetane ring to enhance metabolic stability and solubility. Its amine functionality facilitates straightforward derivatization via amidation or alkylation, while the oxetane moiety exhibits favorable pharmacokinetic properties. The compound demonstrates excellent bench stability and compatibility with common reaction conditions, supporting efficient synthesis of complex heterocyclic scaffolds and API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H315-H318-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   -0.4085
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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