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CS-W001157 4
Total: USD 88.00

(1H-Indol-3-yl)-1-propanamine

  • CAS No. 6245-89-2

  • Cat. No. CS-W018622
  • Purity≥95%
  • MDL No.MFCD00130194

*For research and further manufacturing use only, not for direct human use.

(1H-Indol-3-yl)-1-propanamine|CS-W018622

Structure of 6245-89-2

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General Information

  • CAS No. 6245-89-2
  • Cat. No. CS-W018622
  • Purity ≥95%
  • MDL No. MFCD00130194
  • Storage -20°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₂
  • Molecular Weight 174.24
  • Synonym(s) 1H-indole-3-propylamine
  • SMILES C1=CC=CC2=C1C(=C[NH]2)CCCN

Description

This indole derivative features a flexible propylamine side chain attached to the C3 position of the indole core, enabling integration into bioactive molecules. The pendant amine facilitates conjugation and enhances solubility in polar solvents, supporting its use in medicinal chemistry and peptide synthesis workflows under standard conditions.

Application

(1H-Indol-3-yl)-1-propanamine serves as a versatile building block for the synthesis of indole-based bioactive molecules. Its primary amine functionality enables straightforward derivatization, while the indole core supports diverse transformations including electrophilic substitution and metal-catalyzed coupling reactions. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for medicinal chemistry campaigns and API intermediate development.

Synthesis

  • Route1
    • Indole, ≥99%|CS-1268948
      120-72-9
    • ~%
    • In-stock
      (1H-Indol-3-yl)-1-propanamine|CS-W018622
      6245-89-2

    References

    • Journal of Organic Chemistry, , vol. 66, # 16 p. 5303 - 5316
  • Route2

    References

    • Collection of Czechoslovak Chemical Communications, , vol. 67, # 11 p. 1669 - 1680
  • Route3
    • null|null
      59409-14-2
    • ~%
    • In-stock
      (1H-Indol-3-yl)-1-propanamine|CS-W018622
      6245-89-2

    References

    • Journal of Agricultural and Food Chemistry, , vol. 60, # 32 p. 7792 - 7798

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.81
  • LogP   2.0592
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   3

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