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Structure of 623580-01-8
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2,2-Dimethylpyrrolidine hydrochloride offers a sterically hindered pyrrolidine scaffold with enhanced solubility and stability under standard conditions. This bench-stable salt form facilitates efficient incorporation into synthetic sequences, particularly in catalytic systems and peptide mimetics where conformational rigidity is advantageous.
2,2-Dimethylpyrrolidine hydrochloride serves as a stable, bench-ready nitrogen source for amine-directed functionalizations and asymmetric catalysis. Its tertiary amine functionality exhibits enhanced nucleophilicity and reduced basicity compared to standard pyrrolidines, enabling selective reactivity in enantioselective transformations. The N-alkylated structure improves metabolic stability and solubility, making it well-suited for medicinal chemistry applications involving heterocyclic scaffold elaboration and catalyst design.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501
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Lot numbers can be found on the outside label of a product: